Molecular Playground/IntegrinBeta1

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One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground. Molecular Playground banner: "

Banner: Integrin Beta 1 binds to ECM proteins and allows for 3D in vitro cell migration

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Drag the structure with the mouse to rotate

Contents

Structure

Here are the

Function

Disease

Studying Integrin Beta-1 in vitro

Peyton Lab Research Interests

The Peyton lab studies how cells process chemical and physical cues from the extracellular matrix, and how these interactions play a role in disease progression. By creating synthetic microenvironments, we are able to have tight control of cell-matirx interactions, allowing us to better understand how cells use their integrins to bind to matrix, and what downstream signaling pathways this binding sets off.

References

Proteopedia Page Contributors and Editors (what is this?)

Lauren Barney, Lauren Jansen, Elizabeth Brooks, Michal Harel, Alyssa Schwartz

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