Filamin

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Image:3hop.png
Crystal structure of Human Filamin A complex with phosphate, 3hop

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  • Filamin A (FLNA) has an actin-binding domain (ABD). It crosslinks actin filaments and participates in anchoring of membrane proteins.
  • Filamin B (FLNB) is a human cytoplasmic protein which functions similarly to FLNA and guides proper skeletal development.
  • Filamin C (FLNC) is functionally similar and contains 3 domains: the N-terminal ABD, the C-terminal dimerization domain (DD) and a membrane glycoprotein-binding domain.

For more details on filaminC see Group:MUZIC:FilaminC.

3D structures of filamin

Updated on 06-January-2016

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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