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Neurexin

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Revision as of 10:36, 8 May 2016 by Michal Harel (Talk | contribs)
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Neurexins (NRXN) are a family of presynaptic proteins which bind to the postsynaptic Neuroligin (NLGN) to form a complex which attaches neurons. The NRXN family contains 4 members which are numbered 1 to 4[1]. The NRXN-α contains 6 homologous LNS domains while the NRXN-β contains only LNS6.

See: Neurodevelopmental Disorders
Neuroligin-Neurexin Interaction

3D Structures of Neurexin

08-May-2016

References

  1. ↑ Dean C, Scholl FG, Choih J, DeMaria S, Berger J, Isacoff E, Scheiffele P. Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci. 2003 Jul;6(7):708-16. PMID:12796785 doi:http://dx.doi.org/10.1038/nn1074
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