This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1nxi
From Proteopedia
| |||||||
| Gene: | VC0424 (Vibrio cholerae) | ||||||
| Domains: | PRK11191 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, JenaLib, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Solution structure of Vibrio cholerae protein VC0424
Overview
The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins.
About this Structure
1NXI is a Single protein structure of sequence from Vibrio cholerae. Full crystallographic information is available from OCA.
Reference
Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold., Ramelot TA, Ni S, Goldsmith-Fischman S, Cort JR, Honig B, Kennedy MA, Protein Sci. 2003 Jul;12(7):1556-61. PMID:12824501
Page seeded by OCA on Wed Mar 26 05:59:22 2008
Categories: Single protein | Vibrio cholerae | Cort, J R. | Goldsmith-Fischman, S. | Honig, B. | Kennedy, M A. | NESG, Northeast Structural Genomics Consortium. | Ni, S. | Ramelot, T A. | Ab sandwich | Atcc no. 51394d | Cog 3076 | Nesg target op3 | Northeast structural genomics consortium | Protein structure initiative | Psi | Structural genomic
