Structural highlights 
  Function 
[Q1H3U4_METFK] Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity).[HAMAP-Rule:MF_02128] 
  Evolutionary Conservation 
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.