Structural highlights
4kep is a 1 chain structure with sequence from Mesorhizobium loti. This structure supersedes the now removed PDB entry 3aj0. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , |
| Related: | 3aj3, 4keq |
| Gene: | mlr6805 (Mesorhizobium loti) |
| Activity: | 4-pyridoxolactonase, with EC number 3.1.1.27 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[PDLA_RHILO] Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Hydrolyzes 4-pyridoxolactone to 4-pyridoxic acid. Has lower activity toward N-hexanoyl-D,L-homoserine lactone, but is not active toward 5-pyridoxolactone and gamma-butyrolactone.
