Structural highlights
2o90 is a 1 chain structure with sequence from "bacillus_coli"_migula_1895 "bacillus coli" migula 1895. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Ligands: | |
| Related: | 2nm2, 2nm3, 1dhn, 2dhn, 2oak, 2o9m |
| Gene: | folB ("Bacillus coli" Migula 1895) |
| Activity: | Dihydroneopterin aldolase, with EC number 4.1.2.25 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum |
Function
[FOLB_ECOLI] Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can use L-threo-dihydroneopterin and D-erythro-dihydroneopterin as substrates for the formation of 6-hydroxymethyldihydropterin, but it can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin at appreciable velocity.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
See Also
