2pjy

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Image:2pjy.jpg


PDB ID 2pjy

Drag the structure with the mouse to rotate
, resolution 3.000Å
Gene: TGFB3 (Homo sapiens), TGFBR2 (Homo sapiens), TGFBR1 (Homo sapiens)
Activity: Receptor protein serine/threonine kinase, with EC number 2.7.11.30
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structural basis for cooperative assembly of the TGF-beta signaling complex


Disease

Known disease associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[190230], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[190182], Esophageal cancer OMIM:[190182], Loeys-Dietz syndrome, type 1B OMIM:[190182], Loeys-Dietz syndrome, type 2B OMIM:[190182], Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this Structure

2PJY is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

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