Structural highlights
4uzq is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 4uyu, 4uyw, 4uyz, 4uz1, 4uz5, 4uz6, 4uz7, 4uz9, 4uza, 4uzj, 4uzk, 4uzl, 4wbh |
| Activity: | Carboxylesterase, with EC number 3.1.1.1 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Disease
[WNT7A_HUMAN] Phocomelia, Schinzel type;Fuhrmann syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
Function
[NOTUM_HUMAN] May deacetylate GlcNAc residues on cell surface glycans. [WNT7A_HUMAN] Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity).
