Cyclic GMP-AMP synthase

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Structure of mouse cyclic GMP-AMP synthase C terminal complex with DNA, ATP, Mg+2 (green) and Zn+2 (grey) ions (PDB code 4k97).

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3D structures of cyclic GMP-AMP synthase

Updated on 16-December-2015


References

  1. ↑ Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012, Dec 20. PMID:23258413 doi:10.1126/science.1232458

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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