Structural highlights
Disease
[RGMC_HUMAN] Hemochromatosis type 2. The disease is caused by mutations affecting the gene represented in this entry.
Function
[BMP2_HUMAN] Induces cartilage and bone formation. [RGMC_HUMAN] Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.[UniProtKB:Q7TQ32]