Phosphotransferase

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Phosphotransferase (PT) are enzymes which catalyze phosphorylation reactions. The acceptor group can be alcohol, carboxy, nitrogenous, phosphate or a pair ofd groups.

  • Aminoglycoside PT (AGPT) inactivate aminoglycoside antibiotics by phosphorylation.
  • Phosphoenolpyruvate-protein PT (PEP) catalyzes the phosphorylation of protein histidine residues.
  • Sporulation initiation PT (Spo) are elements in the phosphorelay system which regulates the initiation of sporulation.

See:

3D structures of phosphotransferase

Updated on 03-July-2016

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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