Structural highlights
Publication Abstract from PubMed
Iron-bound structure: The ferric complex of a tetradentate siderophore mimic was synthesized and co-crystallized with the periplasmic binding protein CeuE of Campylobacter jejuni. In addition to electrostatic and hydrogen-bonding interactions between the binding pocket and the substrate, the structure showed direct coordination of two amino acid side chains to the FeIII center (orange, see figure).
Interactions of a Periplasmic Binding Protein with a Tetradentate Siderophore Mimic.,Raines DJ, Moroz OV, Wilson KS, Duhme-Klair AK Angew Chem Int Ed Engl. 2013 Mar 19. doi: 10.1002/anie.201300751. PMID:23512642[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Raines DJ, Moroz OV, Wilson KS, Duhme-Klair AK. Interactions of a Periplasmic Binding Protein with a Tetradentate Siderophore Mimic. Angew Chem Int Ed Engl. 2013 Mar 19. doi: 10.1002/anie.201300751. PMID:23512642 doi:http://dx.doi.org/10.1002/anie.201300751
