1upr

Structural highlights

Function

[PKHA4_HUMAN] Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J. 2000 Oct 1;351(Pt 1):19-31. PMID:11001876