2p8h
From Proteopedia
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, resolution 1.80Å | |||||||
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Ligands: | |||||||
Gene: | BACE1, BACE (Homo sapiens) | ||||||
Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Crystal structure of human beta secretase complexed with inhibitor
About this Structure
2P8H is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul 9;2(7):995-999. PMID:17458843
Page seeded by OCA on Mon Mar 31 04:32:17 2008