Structural highlights
5e8l is a 2 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Related: | 5e8h, 5e8k |
| Gene: | GGPPS1, GGPPS11, GGPS1, At4g36810, C7A10.550 (ARATH) |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[GGPP1_ARATH] Heterodimeric geranyl(geranyl)-diphosphate (GPP) synthase large subunit. In vitro, the large subunit catalyzes mainly the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate while the small subunit alone is inactive. Upon association of the two subunits, the product profile changes and the production of gerany-diphosphate is strongly increased.[1]
References
- ↑ Wang G, Dixon RA. Heterodimeric geranyl(geranyl)diphosphate synthase from hop (Humulus lupulus) and the evolution of monoterpene biosynthesis. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9914-9. doi:, 10.1073/pnas.0904069106. Epub 2009 May 29. PMID:19482937 doi:http://dx.doi.org/10.1073/pnas.0904069106
