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ATP-citrate synthase
From Proteopedia
Function
ATP-citrate synthase (ACS) is part of the citrate cycle. It catalyzes the transformation of ADP, acetyl-CoA and oxaloacetate to ATP, citrate and CoA. ACS is the link between energy metabolism from carbohydrates to the production of fatty acids.
See also Citrate Synthase
Structural highlights
Crystal structures have shown that tartrate binds to ACS in the same binding site.
3D Structures of ATP-citrate synthase
Updated on 08-November-2015
3mwd – hACS + citrate – human
3mwe – hACS + tartrate
3pff - hACS + tartrate + ADP
