Function
Blue copper oxidase CueO (CueO) is an E. coli enzyme which catalyzes the conversion of Cu+1 to Cu+2 resulting in the detoxification of copper by the prevention of its uptake into the cytoplasm.
Relevance
CueO is involved in prevention of oxidative damage in the periplasm.
Structural highlights
The Cu moieties are coordinated by at least 2 histidine residues.
3D structures of blue copper oxidase CueO
Updated on 16-November-2015
3nsf – EcCueO – Escherichia coli
3nt0 – EcCueO (mutant) + Cu+1
3od3, 3pav, 4e9q, 4e9r, 4e9s, 4e9t, 4ef3, 4ner – EcCueO + Cu+2
3nsc, 3nsd, 3uaa, 3uab, 3uac, 3uad, 3uae, 4hak, 4hal – EcCueO (mutant) + Cu+2
3qqx – EcCueO (mutant) + Cu+2 + Cu+1
1n68 – EcCueO + Cu+2 + Cu-Cl-Cu
1pf3 – EcCueO (mutant) + Cu+2 + Cu-Cl-Cu
2fqd, 2fqe, 2fqf, 2fqg, 3pau – EcCueO + Cu+2 + Cu-O-Cu
2yxv, 2yxw, 3nsy – EcCueO (mutant) + Cu+2 + Cu-O-Cu
References
