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Sandbox T1SS T2SS
From Proteopedia
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Description/Function
The Type II secretion system (T2SS) is a secretion pathway found in Gram-negative bacteria. Following transport of a protein from the cytoplasm to the periplasm via the Sec or Tat pathway, the T2SS transports proteins from the periplasm to the extracellular environment[1].
Structure
Each T2SS is made of many general secretory proteins (GSPs). 12-15 GSPs compose one secretory system, and they are often from the same gene cluster and found on the same operon [2]. The T2SS consists of four core components: an outer membrane complex, an inner membrane complex, an ATPase on the cytoplamsic side, and a pseudopilus.
Energetics
References
- ↑ Saier, Milton H. “Protein Secretion Systems in Gram-Negative Bacteria.” 2006. Microbe 1: 414-419.
- ↑ Cianciotto, Nicholas. “Type II secretion: a protein secretion system for all seasons.” 2005. Trends in Microbiology 13: 581-588.
