The chemokine (C-C motif) ligand (CCL2), also known as :
- monocyte chemotactic protein 1 (MCP1)
- small inducible cytokine A2 (SCYA2)
- MCAF
- GDCF-2
- SMC-CF
- HSMCR30
- MGC9434
- GDCF-2
- HC11.
Function
Disease
Relevance
Structural highlights
CCL2 belongs to the superfamily of chemokines, which are proteins involved in immunoregulatory and inflammatory processes. The superfamily can be subdivided into 4 smaller groups, depending on the N-ter arangment of the cysteines. CCL2 is part of the C-C motif group because of the covalent bond made between 2 of the 4 cysteines of the Nter domain.
References
https://fr.wikipedia.org/wiki/CCL2
http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1DOK
http://www.uniprot.org/uniprot/P13500#interaction
