Filamin
From Proteopedia
Image:3hop.png
Crystal structure of Human Filamin A complex with phosphate, 3hop
- Filamin A (FLNA) has an actin-binding domain (ABD). It crosslinks actin filaments and participates in anchoring of membrane proteins.
- Filamin B (FLNB) is a human cytoplasmic protein which functions similarly to FLNA and guides proper skeletal development.
- Filamin C (FLNC) is functionally similar and contains 3 domains: the N-terminal ABD, the C-terminal dimerization domain (DD) and a membrane glycoprotein-binding domain.
For more details on filamin C see Group:MUZIC:FilaminC.
3D structures of filamin
Updated on 06-January-2016
