1r79

Structural highlights

Function

[DGKD_HUMAN] May function as signaling molecule.^[1] Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Kawasaki T, Kobayashi T, Ueyama T, Shirai Y, Saito N. Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha. Biochem J. 2008 Jan 15;409(2):471-9. PMID:17880279 doi:http://dx.doi.org/10.1042/BJ20070755
2. ↑ Kawasaki T, Kobayashi T, Ueyama T, Shirai Y, Saito N. Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha. Biochem J. 2008 Jan 15;409(2):471-9. PMID:17880279 doi:http://dx.doi.org/10.1042/BJ20070755