This is a default text for your page Jacob Applegarth/Sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs.
You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Function
Human GPR40 (hGPR40) is a G-protein coupled receptor that binds free fatty acids to enhance glucose dependent insulin signaling.[3]
Structure
Like most G-protein coupled receptors, hGPR40 contains seven transmembrane helices. In order obtain a crystallized structure of the protein, four (, , , ) were made to increase expression levels and thermal stability of the protein.[3]
Charge Network
hGPR40 has a distinct binding pocket that is established by several key residues. These residues have either a charged or polar R-group that allows them to develop a charge network.
ECl2
Clinical Relevance
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
