1irr

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Template:STRUCTURE 1irr

Solution structure of paralytic peptide of the silkworm, Bombyx mori


Overview

Paralytic peptide of Bombyx mori (BmPP) is one of the multifunctional ENF-peptides; the name of "ENF" is the consensus N-terminal amino acid sequence of the family peptides. We revealed that BmPP significantly possesses growth-blocking activity and plasmatocyte-spreading activity and that its activity profiles are different from those of another ENF-family peptide, namely, the growth-blocking peptide of Pseudaletia separata (PsGBP). We also determined the NMR structures of BmPP and PsGBP under the same conditions, which revealed the structural differences of the first and second beta-turn regions between the two peptides. On the basis of our results, it can be considered that the tertiary structural difference in these peptides may cause their different profiles of growth-blocking activity.

About this Structure

1IRR is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Solution structure of paralytic peptide of silkworm, Bombyx mori., Miura K, Kamimura M, Aizawa T, Kiuchi M, Hayakawa Y, Mizuguchi M, Kawano K, Peptides. 2002 Dec;23(12):2111-6. PMID:12535689 Page seeded by OCA on Fri May 2 20:20:11 2008

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