1zw0

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Image:1zw0.gif

Template:STRUCTURE 1zw0

Crystal structure of the Yersinia Type III Secretion protein YscE


Overview

The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed.

About this Structure

1ZW0 is a Single protein structure of sequence from Yersinia pestis. Full crystallographic information is available from OCA.

Reference

Crystal structure of the Yersinia type III secretion protein YscE., Phan J, Austin BP, Waugh DS, Protein Sci. 2005 Oct;14(10):2759-63. PMID:16195558 Page seeded by OCA on Sat May 3 18:08:45 2008

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