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GLUT3: Glucose Transporter in Mammalian Cells

PDB ID 5c65

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Function

GLUT3 is a glucose transporter that serves highly metabolic and oxidative systems. As such, it is the glucose transporter for neurons and is also known as the neuronal glucose transporter. It plays a key role in metabolism in the brain. GLUT3 also acts as the glucose transporter for cells such as sperm and white blood cells.

Structure

The structure of this protein contains that are composed of two separate chains (alpha helix shown in blue). The structure of GLUT3 also consists of ligands and and is composed of 481 amino acids. It has four different transmembrane segments that are repeated three times (for a total of 12 transmembrane segments).

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