Structural highlights
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The crystal structure of a hypothetical protein MJ0366, derived from Methanocaldococcus jannaschii was solved at 1.9 A resolution using synchrotron radiation. MJ0366 was crystallized as a monomer and has knot structural arrangement. Intriguingly, the solved structure consists of novel 'KNOT' fold conformation. The 31 trefoil knot was observed in the structure. The N-terminal and C-terminal ends did not participate in knot formation.
Crystal structure analysis of a hypothetical protein (MJ0366) from Methanocaldococcus jannaschii revealed a novel topological arrangement of the knot fold.,Thiruselvam V, Kumarevel T, Karthe P, Kuramitsu S, Yokoyama S, Ponnuswamy MN Biochem Biophys Res Commun. 2017 Jan 8;482(2):264-269. doi:, 10.1016/j.bbrc.2016.11.052. Epub 2016 Nov 12. PMID:27845039[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Thiruselvam V, Kumarevel T, Karthe P, Kuramitsu S, Yokoyama S, Ponnuswamy MN. Crystal structure analysis of a hypothetical protein (MJ0366) from Methanocaldococcus jannaschii revealed a novel topological arrangement of the knot fold. Biochem Biophys Res Commun. 2017 Jan 8;482(2):264-269. doi:, 10.1016/j.bbrc.2016.11.052. Epub 2016 Nov 12. PMID:27845039 doi:http://dx.doi.org/10.1016/j.bbrc.2016.11.052
