Structural highlights
Function
ICP27_HHV8P Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular export proteins. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes.[1]
References
- ↑ Malik P, Blackbourn DJ, Clements JB. The evolutionarily conserved Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with REF protein and acts as an RNA export factor. J Biol Chem. 2004 Jul 30;279(31):33001-11. PMID:15155762 doi:10.1074/jbc.M313008200
