4oj2

Structural highlights

Disease

AQP2_HUMAN Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.

Function

AQP2_HUMAN Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

See Also

• Aquaporin 3D structures