2ity

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2ity, resolution 3.42Å

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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH IRESSA

Disease

Known diseases associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this Structure

2ITY is a Single protein structure of sequence from Homo sapiens with IRE as ligand. Active as Receptor protein-tyrosine kinase, with EC number 2.7.10.1 Structure known Active Site: AC1. Full crystallographic information is available from OCA.

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