2itz
From Proteopedia
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CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN L858R MUTATION IN COMPLEX WITH IRESSA
Disease
Known diseases associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
2ITZ is a Single protein structure of sequence from Homo sapiens with CL and IRE as ligands. Active as Receptor protein-tyrosine kinase, with EC number 2.7.10.1 Structure known Active Site: AC2. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Nov 12 22:48:04 2007
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Boggon, T.J. | Eck, M.J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C.H. | CL | IRE | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | Gefitinib | Glycoprotein | Iressa | L858r | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase | Zd1839
