Protein structure
The PrPSc differs from PrPC solely in conformation and is its isoform. The mature PrPC consists of approx. 208 amino acids, arranged as a disordered N-terminus and a globular C-terminal domain consisting of three α-helices and a short, antiparallel β-pleated sheet [1]
References
- ↑ doi: https://dx.doi.org/10.1073/pnas.97.1.145