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Function(s) and Biological Relevance
Inosine-5'-monophosphate dehydrogenase (IMPDH) is the enzyme that catalyzes the rate-limiting step in the de novo guanine nucleotide biosynthetic pathway, converting inosine monophosphate (IMP) to xanthosine monophosphate (XMP) with the reduction of NAD.
Broader Implications
Structural Highlights and Structure-Function Relationships
Energy Transformation
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