1a1c

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Template:STRUCTURE 1a1c

Contents

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL))

Template:ABSTRACT PUBMED 9174343

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1A1C is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study., Charifson PS, Shewchuk LM, Rocque W, Hummel CW, Jordan SR, Mohr C, Pacofsky GJ, Peel MR, Rodriguez M, Sternbach DD, Consler TG, Biochemistry. 1997 May 27;36(21):6283-93. PMID:9174343

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