6v6c

Structural highlights

Disease

GCP6_HUMAN Autosomal recessive chorioretinopathy-microcephaly syndrome. The disease is caused by mutations affecting the gene represented in this entry.

Function

GCP6_HUMAN Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.^[1]

See Also

• Tubulin 3D Structures

References

1. ↑ Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T. GCP5 and GCP6: two new members of the human gamma-tubulin complex. Mol Biol Cell. 2001 Nov;12(11):3340-52. PMID:11694571