Structural highlights
Publication Abstract from PubMed
Free group II introns are infectious retroelements that can bind and insert themselves into RNA and DNA molecules via reverse splicing. Here we report the 3.4-A crystal structure of a complex between an oligonucleotide target substrate and a group IIC intron, as well as the refined free intron structure. The structure of the complex reveals the conformation of motifs involved in exon recognition by group II introns.
Structural basis for exon recognition by a group II intron.,Toor N, Rajashankar K, Keating KS, Pyle AM Nat Struct Mol Biol. 2008 Nov;15(11):1221-2. Epub 2008 Oct 26. PMID:18953333[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Toor N, Rajashankar K, Keating KS, Pyle AM. Structural basis for exon recognition by a group II intron. Nat Struct Mol Biol. 2008 Nov;15(11):1221-2. Epub 2008 Oct 26. PMID:18953333 doi:10.1038/nsmb.1509