This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Salt bridge

From Proteopedia

Revision as of 15:36, 21 November 2021 by Karsten Theis (Talk | contribs)
Jump to: navigation, search

Salt bridges are ionic interactions between oppositely charged side chains in proteins. Sometimes, interactions between charged side chains and bound ions are also call salt bridges. The strength of a salt bridge is strongly dependent on the chemical environment (solvent exposed or buried, nature of the solvent). The contribution of salt bridges to the folded state of the protein is complicated [1].

Examples

Drag the structure with the mouse to rotate

References

  1. ↑ Hendsch ZS, Tidor B. Do salt bridges stabilize proteins? A continuum electrostatic analysis. Protein Sci. 1994 Feb;3(2):211-26. doi: 10.1002/pro.5560030206. PMID:8003958 doi:http://dx.doi.org/10.1002/pro.5560030206
  2. ↑ Donald JE, Kulp DW, DeGrado WF. Salt bridges: geometrically specific, designable interactions. Proteins. 2011 Mar;79(3):898-915. doi: 10.1002/prot.22927. Epub 2011 Jan 5. PMID:21287621 doi:http://dx.doi.org/10.1002/prot.22927

Proteopedia Page Contributors and Editors (what is this?)

Karsten Theis

Retrieved from "http://52.214.119.220/wiki/index.php/Salt_bridge"
Personal tools