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3D Structures of Galactosidase

Updated on 08-March-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

• α-Galactosidase

• • 3hg2, 3gxn, 1r46, 1r47, 3s5y, 3s5z – hAgal A - human
    
  • 3lx9, 3lxa, 3lxb, 3lxc, 3tv8 - hAgal A (mutant)
    
  • 3h53 - hAgal B (mutant)
    
  • 1uas – Agal – rice
    
  • 3lrk – yAgal 1 (mutant) – yeast
    
  • 3lrl, 3lrm – yAgal 1 (mutant) + polysaccharide
    
  • 1zy9, 5m0x – TmAgal – Thermotoga maritima
    
  • 3a24 – BtAgal – Bacterioides thetaiotamicron
    
  • 3a5v – Agal I – Mortierella vinacea
    
  • 3mi6 – Agal – Lactobacillus brevis
    
  • 1szn – HjAgal – Hypocrea jecorina
    
  • 2xn0, 2xn1 – LaAgal – Lactobacillus acidophilus
    
  • 4fnp, 4ojy – GsAgal (mutant) – Geobacillus stearothermophilus
    
  • 4fnq, 4fnr, 4oif – GsAgal
    
  • 4xpo - PsBgal – Pedobacter saltans
    
  • 4xpr - PsAgal (mutant)
    
  • 6f4c - Agal – Nicotiana benthamiana
    
  • 6jhp - Agal – Paecilomyces
    
  • 6lcj - TtAgal – Thermus thermophilus
    
  • 6phu – SpAgal – Streptococcus pneumoniae<br />
  • 6y2k - Agal – Marinomonas
    

• α-galactosidase binary complex

• • 3h54 - hAgal B (mutant) + polysaccharide
    
  • 3h55 - hAgal B (mutant) + galactose
    
  • 3igu - hAgal B (mutant) + intermediate
    
  • 3hg3, 3hg5 - hAgal A (mutant) + galactose
    
  • 3gxp - hAgal A + galactose
    
  • 3hg4 – hAgal A + intermediate
    
  • 3gxt – hAgal A + imino sugar
    
  • 4nxs - hAgal + jirimycin derivative
    
  • 6ibk, 6ibm, 6ibr, 6ibt - hAgal A + trisaccharide + cyclosulfamidate
    
  • 7exq, 7exr - Agal + saccharide – Arabidopsis thaliana
    
  • 1t0o – HjAgal + galactose
    
  • 2xn2 - LaAgal + galactose
    
  • 4xpp - PsAgal + galactose
    
  • 4xpq - PsAgal + fucose
    
  • 4xps - PsAgal (mutant) + galactopyranoside derivative
    
  • 4fns - GsAgal (mutant) + jirimycin derivative
    
  • 4fnt, 4fnu – GsAgal + galactoside
    
  • 5e1q - BtAgal + Gal-Lac
    
  • 5m12, 5m16, 5m1i, 6gx8, 6gwg, 6gvd - TmAgal + sugar
    
  • 6gwf, 6gta - TmAgal (mutant) + sugar
    
  • 6lck, 6lcl - TtAgal + saccharide
    
  • 6phv - SpAgal + galactopyranoside derivative
    
  • 6phw, 6phx, 6phy, 6pi0 - SpAgal (mutant) + oligosaccharide
    

• β-Galactosidase

• • 3w5f – toBgal – tomato
    
  • 5iaz - rBgal C-terminal - NMR
    
  • 3og2 – TrBgal – Trichoderma reesei
    
  • 1hn1, 1dp0, 1f4a, 1f4h, 4v41, 4v40, 4ttg, 6drv - EcBgal - Escherichia coli
    
  • 3muy, 3i3e, 3iap, 3iaq, 3dym, 3dyp, 1px3, 3sep, 3t0a, 3t2o, 3vd3, 3vd5, 3vda, 4duv – EcBgal (mutant)
    
  • 3j7h, 6cvm, 6drv, 6x1q – EcBgal – cryo EM
    
  • 3dec, 3d3a, 3bga, 5mt2, 5mui, 5muj, 6euf, 6euj – BtBgal
    
  • 6etz, 6h1p, 6zjv - ArBgal – Arthrobacter
    
  • 1yq2, 6se8, 6zjp - ArBgal (mutant)
    
  • 1uwi, 4eam, 5i3d - SsBgal (mutant) - Sulfolobus solfataricus
    
  • 1uwq, 1gow – SsBgal
    
  • 1kwg – TtBgal – Thermus thermophilus
    
  • 1tg7 – PeBgal – Penicillium
    
  • 3tts, 4mad, 7cwi – BcBgal – Bacillus circulans
    
  • 4ypj - BcBgal (mutant)
    
  • 4ha3, 4ha4 – Bgal – Acidilobus saccharovorans
    
  • 3wq8, 6jow – Bgal – Pyrococcus furiosus
    
  • 4cu6, 4cu8 – SpBgal catalytic module residues 137-985– Streptococcus pneumoniae
    
  • 4cu9 – SpBgal carbohydrate-binding module II residues 1822-1998
    
  • 4cua – SpBgal carbohydrate-binding module I residues 1463-1645
    
  • 5xb7 - BaBgal – Bifidobacterium animalis
    
  • 4uoq - BaBgal (mutant)
    
  • 5vym - Bgal – Bifidobacterium adolescentis
    
  • 5nav, 5naq - Bgal – Lactobacillus plantarum
    
  • 5yhs - BacBgal – Bacillus
    
  • 3ob8, 3oba – Bgal – Kluyveromyces lactis
    
  • 5dfa - GsBgal (mutant)
    
  • 5dmy, [[6quc], 7nit] - BbBgal – Bifidobacterium bifidum
    
  • 5e9a - Bgal - Rahnella
    
  • 5euv - ParBgal - Paracoccus
    
  • 5ifp - AnBgal – Aspergillus niger
    
  • 6mvh - Bgal – Roseburia hominis
    
  • 6hpd - Bgal – Formosa agariphila
    
  • 6s6z, 6sd0 - TmBgal – Cryo EM
    
  • 6lvw - Bgal – Halorubrum lacusprofundi
    
  • 6u7i - FpBgal – Faecaibavterium prausnitzii
    
  • 6u7j - Bgal – Clostridium
    
  • 6m4e - Bgal – Hamamotoa singularis
    
  • 6ld6 - BdBgal – Bifidobacterium dentium
    
  • 6ec6, 6jz1 - RgBgal – Ruminococcus gnavus
    
  • 7kmn - XcBgal – Xanthomonas citri
    
  • 4d1i - CjBgal – Cellvibrio japonicus
    
  • 7f1n - Bgal - Thermofilum
    
  • 7sf2 - Bgal – Bacterioides cellulosilyticus
    

• β-Galactosidase binary complex with galactose

• • 3thc - hBgal + galactose
    
  • 3wf3 - hBgal + galactose + NAG
    
  • 3w5g, 6ik5 - toBgal + galactose
    
  • 6ik6, 6ik7, 6ik8 - toBgal (mutant) + galactobiose
    
  • 1kwk – TtBgal + galactose
    
  • 3ogr – TrBgal + galactose
    
  • 3e1f, 1jz7 - EcBgal (mutant) + galactose
    
  • 3t09, 3t0d, 3t2q, 3vd7, 3vdb - EcBgal (mutant) + galactose derivative
    
  • 4iug - Bgal + galactose – Aspergillus oryzae
    
  • 3tty - BcBgal + galactose
    
  • 4cub, 4e8c, 4e8d – SpBgal carbohydrate-binding module I + galactose
    
  • 4cuc – SpBgal catalytic module (mutant) + galactose
    
  • 4uni - BaBgal + galactose
    
  • 4uoz - BaBgal (mutant) + galactose
    
  • 4ucf, 4uzs, 6qub, 6qud - BbBgal + galactose
    
  • 5ldr - ParBgal + galactose
    
  • 6eon - BtBgal + galactose
    
  • 1xc6 - PeBgal + galactose
    
  • 6sed - ArBgal + galactose
    
  • 6zjq, 6zjs, 6zjw - ArBgal (mutant) + galactose
    
  • 6zju - ArBgal (mutant) + saccharose
    
  • 5yif - BacBgal (mutant) + galactose
    
  • 7kmo - XcBgal + galactose
    
  • 6eui - BtBgal + galactose
    

• β-Galactosidase other complexes

• • 3thd – hBgal + jirimycin derivative
    
  • 3wez - hBgal + NOEV
    
  • 3wf0, 3wf1 - hBgal + pyrimidine derivative
    
  • 3wf4 - hBgal (mutant) + pyridine derivative
    
  • 3wf2 - hBgal + piperidine derivative
    
  • 7kdv - Bgal + cathepsin A – mouse – Cryo EM
    
  • 7bzm - rBgal + glucoimidazole
    
  • 3ogs - TrBgal + IPTG
    
  • 3ogv – TrBgal + inhibitor
    
  • 2ceq, 1uwr, 1uws, 1uwt, 1uwu, 2cer - SsBgal + inhibitor
    
  • 4ean, 5ixe – SsBgal + indole derivative
    
  • 3muz, 3i3d, 3dyo, 1px4, 1jyx, 3t08, 3t0b, 3t2p, 3vd4, 3vd9, 3vdc- EcBgal (mutant) + IPTG
    
  • 3mv0, 3i3b, 3czj, 4v45, 1jz2, 1jz3, 1jz4, 1jz5, 1jz6 - EcBgal (mutant) + intermediate
    
  • 3mv1 - EcBgal (mutant) + guanidinium
    
  • 1jyn, 4v44, 1jz8 - EcBgal (mutant) + lactose derivative
    
  • 1jyn, 1jyw, 1jyv - EcBgal (mutant) + substrate
    
  • 5a1a - EcBgal + inhibitor – Cryo-EM
    
  • 1jz6 - EcBgal (mutant) + inhibitor
    
  • 4duw - EcBgal (mutant) + allolactose
    
  • 6tsk - EcBgal + ribose – Cryo EM
    
  • 4dux - EcBgal (mutant) + ribose
    
  • 6tte - EcBgal + galactopyranoside derivative – Cryo EM
    
  • 6tsh - EcBgal + jirimycin derivative – Cryo EM
    
  • 6kuz, 7brs, 7btk - EcBgal (mutant) + probe
    
  • 6leg, 6lej, 6lel, 6lem - EcBgal + Gauche drug
    
  • 4ckd – EcBgal + antibody
    
  • 4cu7 - SpBgal catalytic module + Gaucher drug
    
  • 6nzg - BuBgal + aziridine derivative – Bacterioides uniformis
    
  • 6seb, 6sec - ArBgal + galactopyranoside derivative
    
  • 6se9, 6sea - ArBgal (mutant) + lactose
    
  • 6zjx - ArBgal (mutant) + saccharose
    
  • 6zjr, 6zjt - ArBgal (mutant) + lactulose
    
  • 7cwd - BcBgal + disaccharide
    
  • 6ld0, 6ldb, 6ldc, 6ldd - BdBgal + Gauche drug
    
  • 6jz2, 6jz6, 6jz7 - RgBgal + Gauche drug
    
  • 6jz4, 6jz8 - RgBgal + glucaro lactone
    
  • 5mgc, 5mgd - RgBgal (mutant) + disaccharise
    
  • 6jz3 - RgBgal + drug
    
  • 6mvf - FpBgal + FMN
    
  • 6d4o - Bgal + glucuronic acid derivative – Lachnospira eligens
    
  • 6euh - BtBgal + drug
    
  • 6eug - BtBgal + galactoimidazole
    
  • 7zvo - BtBgal + Ser + Ala
    
  • 5jaw, 6tbf, 6tbg, 6tbh, 6tbi, 6tbj, 6tbk - CjBgal + inhibitor
    
  • 4d1j - CjBgal + drug
    
  • 5ift, 5ihr, 5juv - AnBgal (mutant) + saccharide
    

• Endo-1,4-β-galactosidase

• • 2xom, 2xon – TmEbgal carbohydrate-binding domain + β-galactotriose
    
  • 1ups – Ebgal - Clostridium perfringens
    
  • 2ygl, 2ygm – SpEbgal blood group A & B cleaving
    
  • 4bf7 – Ebgal – Emericella nidulans
    
  • 7pmo – Rggal
    
  • 7q1w, 7q20 – Rggal (mutant) + polysaccharide
    

• 3,6-anhydro-α-L-galactosidase

• • 3p2n, 5opq – AAgal – Zobellia galactanivorans
    
  • 4ak5, 7ljj – BpAAgal – Bacterioides plebeius
    
  • 4ak6 – BpAAgal (mutant)
    
  • 4ak7, 7lnp – BpAAgal (mutant) + polysaccharide
    
  • 7lk7 – BpAAgal + galactose
    

• 6-phospho-β-D-galactosidase

• • 2pbg, 3pbg, 4pbg, 1pbg – Pgal (mutant) – Lactococcus lacti
    
  • 2v4v – gal GH59 – Clostridium cellulolyticum
    
  • 4zep – GsPgal + phospho-glucose
    
  • 7m1r – Pgal – Bacillus licheiformis
    

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