Structural highlights
Function
APOC1_HUMAN Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Westerterp M, Berbee JF, Delsing DJ, Jong MC, Gijbels MJ, Dahlmans VE, Offerman EH, Romijn JA, Havekes LM, Rensen PC. Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification. J Lipid Res. 2007 Jun;48(6):1353-61. Epub 2007 Mar 5. PMID:17339654 doi:http://dx.doi.org/10.1194/jlr.M700024-JLR200
