Structural highlights
Function
RBM11_HUMAN Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Pedrotti S, Busa R, Compagnucci C, Sette C. The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator. Nucleic Acids Res. 2012 Feb;40(3):1021-32. doi: 10.1093/nar/gkr819. Epub 2011 Oct, 7. PMID:21984414 doi:http://dx.doi.org/10.1093/nar/gkr819
