7zuf

Structural highlights

Function

[GAG_SCVLB] Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, about 40 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers. The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm (By similarity).