1hsg

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Image:1hsg.png

1hsg, resolution 2.00Å ()

Ligands:

Gene:

HIV-1 PROTEASE FROM THE NY5 ISOLATE (Human immunodeficiency virus 1)

Structural annotation:
Resources:	CATH : 1Hsga00, 1Hsgb00 InterPro : Ipr010659, Ipr010999, Ipr001995, Ipr008916, Ipr010661, Ipr002156, Ipr001878, Ipr000071, Ipr000721, Ipr012337, Ipr001037, Ipr009007, Ipr001969, Ipr008919, Ipr003308, Ipr000477, Ipr013084, Ipr001584 Pfam : PF00077 SCOP : d1hsga_, d1hsgb_ UniProt : P03367

Functional annotation:
Cellular component:	cytoplasm viral nucleocapsid nucleus membrane viral capsid virion
Biological process:	viral reproduction viral procapsid maturation DNA integration proteolysis DNA recombination RNA-dependent DNA replication transposition, DNA-mediated
Molecular function:	hydrolase activity nucleotidyltransferase activity ribonuclease H activity nucleic acid binding aspartic-type endopeptidase activity peptidase activity endonuclease activity DNA binding transferase activity RNA-directed DNA polymerase activity metal ion binding structural molecule activity RNA binding magnesium ion binding DNA-directed DNA polymerase activity zinc ion binding nuclease activity catalytic activity integrase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES

Template:ABSTRACT 7929352

About this Structure

1HSG is a Single protein structure of sequence from Human immunodeficiency virus 1. The following page contains interesting information on the relation of 1HSG with [HIV-1 Protease]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:30:10 2008