7x06

Structural highlights

Function

CHS1_PHYSP Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (PubMed:36131020). Involved in mycelial growth, sporangial production, zoospore release and pathogenesis (PubMed:31314944).^{[1] [2]}

References

1. ↑ Cheng W, Lin M, Qiu M, Kong L, Xu Y, Li Y, Wang Y, Ye W, Dong S, He S, Wang Y. Chitin synthase is involved in vegetative growth, asexual reproduction and pathogenesis of Phytophthora capsici and Phytophthora sojae. Environ Microbiol. 2019 Dec;21(12):4537-4547. PMID:31314944 doi:10.1111/1462-2920.14744
2. ↑ Chen W, Cao P, Liu Y, Yu A, Wang D, Chen L, Sundarraj R, Yuchi Z, Gong Y, Merzendorfer H, Yang Q. Structural basis for directional chitin biosynthesis. Nature. 2022 Oct;610(7931):402-408. PMID:36131020 doi:10.1038/s41586-022-05244-5