4pwy

Structural highlights

Disease

CMKMT_HUMAN Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome.

Function

CMKMT_HUMAN Catalyzes the trimethylation of 'Lys-116' in calmodulin.^[1]

References

1. ↑ Magnani R, Dirk LM, Trievel RC, Houtz RL. Calmodulin methyltransferase is an evolutionarily conserved enzyme that trimethylates Lys-115 in calmodulin. Nat Commun. 2010 Jul 27;1:43. doi: 10.1038/ncomms1044. PMID:20975703 doi:http://dx.doi.org/10.1038/ncomms1044