8ovl

Structural highlights

Function

COPA_LEGPH Couples the hydrolysis of ATP with the export of copper.^{[1] [2] [3]}

References

1. ↑ Andersson M, Mattle D, Sitsel O, Klymchuk T, Nielsen AM, Moller LB, White SH, Nissen P, Gourdon P. Copper-transporting P-type ATPases use a unique ion-release pathway. Nat Struct Mol Biol. 2013 Dec 8. doi: 10.1038/nsmb.2721. PMID:24317491 doi:http://dx.doi.org/10.1038/nsmb.2721
2. ↑ Placenti MA, Roman EA, González Flecha FL, González-Lebrero RM. Functional characterization of Legionella pneumophila Cu(+) transport ATPase. The activation by Cu(+) and ATP. Biochim Biophys Acta Biomembr. 2022 Feb 1;1864(2):183822. PMID:34826402 doi:10.1016/j.bbamem.2021.183822
3. ↑ Gourdon P, Liu XY, Skjorringe T, Morth JP, Moller LB, Pedersen BP, Nissen P. Crystal structure of a copper-transporting PIB-type ATPase. Nature. 2011 Jun 29;475(7354):59-64. doi: 10.1038/nature10191. PMID:21716286 doi:10.1038/nature10191