8v89

Structural highlights

Disease

ACHA7_HUMAN 15q13.3 microdeletion syndrome.

Function

C562_ECOLX Electron-transport protein of unknown function.ACHA7_HUMAN After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.