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The Amylin Receptor(AMYR)

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Introduction 2 Overview and Function 2.1 Role of Amylin 2.2 Amylin Peptide Structure 3 Structure 3.1 Structure Overview 3.2 Amidated C-Terminus 3.3 G-Alpha-TMD Interaction 3.4 N Terminus Dusulfide 4 Mechanism of Activation 4.1 Two Domain Model of Amylin Binding 5 Disease 6 Relevance 7 Structural highlights Introduction Overview and Function Role of Amylin Amylin history, role, etc Amylin Peptide Structure Figure Legend Structure Structure Overview Amidated C-Terminus G-Alpha-TMD Interaction N Terminus Dusulfide Mechanism of Activation Two Domain Model of Amylin Binding Figure Legend Disease [1] Relevance Structural highlights Figure Legend [1] [2] This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

References

1. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
2. ↑ Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. A structural basis for amylin receptor phenotype. Science. 2022 Mar 25;375(6587):eabm9609. PMID:35324283 doi:10.1126/science.abm9609

Student Contributors

• Ty Vander Eide
• Andrew Helmerich
• Ben Whiteside