Structural highlights
Disease
COHA1_HUMAN Late-onset junctional epidermolysis bullosa;Intermediate generalized junctional epidermolysis bullosa;Epithelial recurrent erosion dystrophy;Localized junctional epidermolysis bullosa. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
Function
COHA1_HUMAN May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.
