Structural highlights
Disease
OPSB_HUMAN Tritanopia. The disease is caused by variants affecting the gene represented in this entry.
Function
OPSB_HUMAN Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (Probable). Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity). Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity). May increase spectral sensitivity in dim light (By similarity).[UniProtKB:P51491][1]
References
- ↑ Nathans J, Thomas D, Hogness DS. Molecular genetics of human color vision: the genes encoding blue, green, and red pigments. Science. 1986 Apr 11;232(4747):193-202. PMID:2937147 doi:10.1126/science.2937147
