9ukv

Structural highlights

Function

MURJ_ECOLI Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.[HAMAP-Rule:MF_02078]^{[1] [2] [3]}

References

1. ↑ Inoue A, Murata Y, Takahashi H, Tsuji N, Fujisaki S, Kato J. Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli. J Bacteriol. 2008 Nov;190(21):7298-301. doi: 10.1128/JB.00551-08. Epub 2008 Aug, 15. PMID:18708495 doi:http://dx.doi.org/10.1128/JB.00551-08
2. ↑ Ruiz N. Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15553-7. doi:, 10.1073/pnas.0808352105. Epub 2008 Oct 1. PMID:18832143 doi:http://dx.doi.org/10.1073/pnas.0808352105
3. ↑ Sham LT, Butler EK, Lebar MD, Kahne D, Bernhardt TG, Ruiz N. Bacterial cell wall. MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis. Science. 2014 Jul 11;345(6193):220-2. doi: 10.1126/science.1254522. PMID:25013077 doi:http://dx.doi.org/10.1126/science.1254522